Cal/EPA Logo
  Cal/EPA


California
Environmental
Protection
Agency

Department of Pesticide Regulation Logo

Department of
Pesticide
Regulation

1020 N Street
Sacramento, CA
95814-5624
(916) 445-4300


Branches:

Pesticide
Registration

Medical
Toxicology

Worker Health
and Safety

Environmental
Monitoring and
Pest Management

Pesticide
Enforcement

Information
Systems

Audits

Resources Management



  California Notice 97-5
  POST UNTIL January 15, 1998

NOTICE OF INITIATION OF REEVALUATION OF PESTICIDE PRODUCTS

Pursuant to Articles 8 and 12 (Title 3) of the California Code of Regulations, the Director of the Department of Pesticide Regulation (DPR), notices its decision to initiate a reevaluation of pesticide products. Interested persons may comment on this decision up to and including the date shown on the top-right corner of this notice to the Department of Pesticide Regulation, Pesticide Registration Branch, 1020 N Street, Room 332, Sacramento, California 95814.

REEVALUATION

DPR commences reevaluation of the following pesticide products without further notice. The products included in this reevaluation
are rodenticides that contain one percent or more of the active ingredient diphacinone.

Registrant


Brand Name
U.S. EPA Reg. No.


Bell Laboratories, Inc. 1% Diphacinone Concentrate 12455-71-AA
Haco, Inc. Diphacin 110-A Concentrate 2393-493-AA

BASIS OF REEVALUATION

The pesticide active ingredient diphacinone is registered in California for use in and around homes, agricultural and industrial buildings, and in sewers for the control of Norway rats, roof rats, and house mice. DPR registers 51 products containing diphacinone. Of the currently registered products, 49 are intended for end-use and contain 0.2 percent or less diphacinone. Containing one percent and two percent diphacinone, the two remaining products are concentrates intended for use in the formulation of end-use rodenticides.

DPR initiates this reevaluation based on its review of acute toxicity data recently submitted to support the registration of Bell Laboratories, Inc.'s product, 1% Diphacinone Concentrate®. DPR found the submitted acute dermal toxicity and primary dermal irritation studies to be unacceptable. Without the submission of acceptable acute toxicity studies, DPR is unable to determine whether the precautionary statement currently on the label of the product adequately identifies acute toxicity hazards.

After a search of the database, DPR determined that no acute toxicity studies are on file to support the registration of Haco, Inc.'s product, Diphacin 110-A Concentrate®. Haco's product contains two percent diphacinone. Without the results of acceptable acute toxicity studies, DPR cannot determine whether the precautionary statement currently on the product label adequately identifies acute toxicity hazards.

Pursuant to this reevaluation, DPR intends to ask the registrants of both products to submit acceptable acute toxicity studies. Based upon the results of the acute toxicity studies, DPR will determine whether the product labels adequately identify acute toxicity hazards.

For information, please contact Ms. Ann Prichard, Senior Environmental Research Scientist, Pesticide Registration Branch, by E-mail at (aprichard@cdpr.ca.gov) or by telephone at (916) 324-3931.


original signed by Barry Cortez


11-25-97


Barry Cortez, Chief
Pesticide Registration Branch
(916) 445-4377

Date


cc: Ms. Ann Prichard

California State Seal

Pete Wilson
Governor

Peter Rooney

Secretary for
Environmental
Protection



James
W. Wells
Director